| 14. Round | 09/08/2021 | Varbergs BoIS | - | IK Sirius | 0:0 | ||||
| 15. Round | 16/08/2021 | IK Sirius | - | AIK Solna | 0:1 |  |
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| 16. Round | 22/08/2021 | Örebro SK | - | IK Sirius | 1:1 | ||||
| 17. Round | 29/08/2021 | IK Sirius | - | Djurgårdens IF | 1:0 | ||||
| 19. Round | 18/09/2021 | Degerfors IF | - | IK Sirius | 1:2 | ||||
| 20. Round | 22/09/2021 | IK Sirius | - | IFK Norrköping | 2:4 | ||||
| 21. Round | 27/09/2021 | Halmstads BK | - | IK Sirius | 1:1 | ||||
| 23. Round | 16/10/2021 | IK Sirius | - | Varbergs BoIS | 2:1 | ||||
| 24. Round | 24/10/2021 | IF Elfsborg | - | IK Sirius | 3:0 | ||||
| 25. Round | 27/10/2021 | IK Sirius | - | Hammarby IF | 0:1 | ||||
| 26. Round | 30/10/2021 | IK Sirius | - | Malmö FF | 2:3 |  |
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| 27. Round | 06/11/2021 | Mjällby AIF | - | IK Sirius | 2:3 | |
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| 28. Round | 21/11/2021 | IK Sirius | - | IFK Göteborg | 3:3 | |
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| 29. Round | 29/11/2021 | IK Sirius | - | BK Häcken | 3:0 | ||||
| 30. Round | 04/12/2021 | AIK Solna | - | IK Sirius | 4:2 | |
Sweden