| 2. Round | 04/09/2022 | Tulancingo | - | Lobos ULMX | 0:1 | ||||
| 3. Round | 08/09/2022 | Lobos ULMX | - | Inter de Querétaro | 1:0 |  |
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| 4. Round | 11/09/2022 | Saltillo FC | - | Lobos ULMX | 3:1 | ||||
| 5. Round | 18/09/2022 | Lobos ULMX | - | Correcaminos UAT II | 2:2 | ||||
| 7. Round | 29/09/2022 | Lobos ULMX | - | Gavilanes de Matamoros | 0:5 | ||||
| 9. Round | 09/10/2022 | Lobos ULMX | - | Colima FC | 3:2 |
Mexico