| 3. Round | 03/10/2020 | Alacranes de Durango | - | Gavilanes de Matamoros | 5:0 | ||||
| 4. Round | 10/10/2020 | Gavilanes de Matamoros | - | Cimarrones de Sonora II | 1:0 | ||||
| 5. Round | 31/10/2020 | Saltillo FC | - | Gavilanes de Matamoros | 0:0 | ||||
| 9. Round | 22/11/2020 | Mazorqueros | - | Gavilanes de Matamoros | 1:2 | ||||
| 2. Round | 28/11/2020 | Gavilanes de Matamoros | - | Tuzos de la UAZ | 1:0 | ||||
| 10. Round | 06/12/2020 | Gavilanes de Matamoros | - | Atlético San Luis II | 1:0 | ||||
| 8. Round | 09/12/2020 | Gavilanes de Matamoros | - | Mineros de Fresnillo FC | 3:0 |  |
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| 16. Round | 12/02/2021 | Gavilanes de Matamoros | - | Saltillo FC | 2:1 | ||||
| 17. Round | 22/02/2021 | Leones Negros II | - | Gavilanes de Matamoros | 0:1 | ||||
| 20. Round | 20/03/2021 | Gavilanes de Matamoros | - | Mazorqueros | 1:0 | ||||
| 22. Round | 10/04/2021 | Gavilanes de Matamoros | - | Reboceros de La Piedad | 3:0 |
Mexico