| 3. Round | 30/09/2000 | Olympiakos Piraeus | - | Ionikos Nikea | 3:3 | ||||
| 5. Round | 05/11/2000 | Panachaiki GE | - | Ionikos Nikea | 2:3 | ||||
| 6. Round | 11/11/2000 | Ionikos Nikea | - | PS Kalamata | 4:1 | ||||
| 7. Round | 19/11/2000 | PAS Giannina | - | Ionikos Nikea | 1:1 | ||||
| 10. Round | 08/12/2000 | Ionikos Nikea | - | OFI Heraklion | 1:0 | ||||
| 12. Round | 02/01/2001 | Panathinaikos | - | Ionikos Nikea | 4:1 |
Ukraine