| 1. Round | 29/08/2021 | Bnei Sachnin FC | - | Maccabi Tel Aviv | 3:1 | ||||
| 5. Round | 03/10/2021 | Maccabi Tel Aviv | - | Hapoel Jerusalem | 1:0 |  |
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| 6. Round | 16/10/2021 | Maccabi Netanya | - | Maccabi Tel Aviv | 4:2 | ||||
| 7. Round | 25/10/2021 | Maccabi Tel Aviv | - | FC Ashdod | 0:2 | ||||
| 9. Round | 07/11/2021 | Maccabi Tel Aviv | - | Hapoel Tel Aviv | 1:1 | ||||
| 10. Round | 28/11/2021 | Hapoel Haifa | - | Maccabi Tel Aviv | 1:3 | ||||
| 11. Round | 01/12/2021 | Maccabi Tel Aviv | - | Hapoel Nof HaGalil | 1:1 | ||||
| 12. Round | 05/12/2021 | Beitar Jerusalem | - | Maccabi Tel Aviv | 1:2 | ||||
| 13. Round | 13/12/2021 | Maccabi Tel Aviv | - | Hapoel Hadera | 3:0 | ||||
| 14. Round | 22/12/2021 | Maccabi Tel Aviv | - | Bnei Sachnin FC | 1:1 | ||||
| 15. Round | 27/12/2021 | Maccabi Petach-Tikva | - | Maccabi Tel Aviv | 1:2 |  |
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| 16. Round | 03/01/2022 | Maccabi Haifa | - | Maccabi Tel Aviv | 3:2 | ||||
| 18. Round | 15/01/2022 | Hapoel Jerusalem | - | Maccabi Tel Aviv | 1:3 | ||||
| 19. Round | 22/01/2022 | Maccabi Tel Aviv | - | Maccabi Netanya | 2:2 | |
Panama