| 1. Round | 11/01/2021 | CF Pachuca [U17] | - | FC Juárez [U17] | 2:0 | ||||
| 2. Round | 18/01/2021 | Club León [U17] | - | CF Pachuca [U17] | 3:1 |  |
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| 3. Round | 25/01/2021 | CF Pachuca [U17] | - | Cruz Azul [U17] | 3:2 | |
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| 4. Round | 29/01/2021 | Mazatlán FC [U17] | - | CF Pachuca [U17] | 1:1 | ||||
| 5. Round | 04/02/2021 | Gallos Blancos [U17] | - | CF Pachuca [U17] | 1:6 | |
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| 6. Round | 15/02/2021 | CF Pachuca [U17] | - | Atlas Guadalajara [U17] | 3:1 | |
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| 7. Round | 22/02/2021 | CF Pachuca [U17] | - | Deportivo Guadalajara [U17] | 3:1 | ||||
| 8. Round | 27/02/2021 | CF América [U17] | - | CF Pachuca [U17] | 0:3 | ||||
| 9. Round | 04/03/2021 | Club Necaxa [U17] | - | CF Pachuca [U17] | 0:2 | ||||
| 13. Round | 04/04/2021 | Pumas UNAM [U17] | - | CF Pachuca [U17] | 5:3 | |
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| 14. Round | 12/04/2021 | CF Pachuca [U17] | - | Puebla FC [U17] | 5:1 | |
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| 15. Round | 18/04/2021 | CF Monterrey [U17] | - | CF Pachuca [U17] | 2:4 | |
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| 16. Round | 26/04/2021 | CF Pachuca [U17] | - | Santos Laguna [U17] | 4:2 | |
Mexico