| Quarter-finals | 11/05/2022 | Achuapa | - | CSD Municipal | 0:1 |  |
|||
| Quarter-finals | 14/05/2022 | CSD Municipal | - | Achuapa | 2:0 | |
|||
| Semi-finals | 19/05/2022 | Deportivo Guastatoya | - | CSD Municipal | 1:1 | |
|||
| Semi-finals | 22/05/2022 | CSD Municipal | - | Deportivo Guastatoya | 1:1 | ||||
| Final | 26/05/2022 | CSD Municipal | - | Comunicaciones | 0:1 |
Argentina