 |
 |
|
|
| 1st(1st leg) | Deportivo Malacateco | - | Comunicaciones | 1:1 (0:0) | ||
| 2nd (2nd leg) | Comunicaciones | - | Deportivo Malacateco | 0:0 (0:0) | ||
| 1st(1st leg): 18/05/2022 19:00 | 2nd (2nd leg): 22/05/2022 01:00 | Winner: Comunicaciones | ||||
| 1st(1st leg) | Deportivo Guastatoya | - | CSD Municipal | 1:1 (0:0) | ||
| 2nd (2nd leg) | CSD Municipal | - | Deportivo Guastatoya | 1:1 (0:1) | ||
| 1st(1st leg): 19/05/2022 18:00 | 2nd (2nd leg): 22/05/2022 22:00 | |||||
