| 2. Round | 02/08/2020 | UANL Tigres | - | CF Pachuca | 1:1 |  |
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| 5. Round | 15/08/2020 | Puebla FC | - | CF Pachuca | 0:1 | ||||
| 7. Round | 30/08/2020 | Deportivo Guadalajara | - | CF Pachuca | 0:0 | ||||
| 10. Round | 15/09/2020 | CF Pachuca | - | CF Monterrey | 1:1 | ||||
| 13. Round | 04/10/2020 | FC Juárez | - | CF Pachuca | 1:1 | ||||
| 14. Round | 19/10/2020 | Santos Laguna | - | CF Pachuca | 1:1 | ||||
| 16. Round | 31/10/2020 | Club Tijuana | - | CF Pachuca | 0:2 | ||||
| 17. Round | 07/11/2020 | CF Pachuca | - | Club Necaxa | 0:1 |
Mexico