| 1. Round | 14/08/2021 | RWD Molenbeek | - | Royal Excel Mouscron | 3:1 | ||||
| 2. Round | 21/08/2021 | Royal Excel Mouscron | - | Lommel SK | 0:1 |  |
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| 4. Round | 10/09/2021 | SK Deinze | - | Royal Excel Mouscron | 3:1 | ||||
| 5. Round | 18/09/2021 | Royal Excel Mouscron | - | Excelsior Virton | 1:1 | ||||
| 6. Round | 26/09/2021 | Royal Excel Mouscron | - | KVC Westerlo | 1:2 |
Senegal