| 1. Round | 28/08/2022 | Mexicali FC | - | Tuzos de la UAZ | 0:3 | ||||
| 5. Round | 18/09/2022 | Mexicali FC | - | Los Cabos United | 0:2 | ||||
| 6. Round | 24/09/2022 | Leones Negros II | - | Mexicali FC | 5:0 | ||||
| 8. Round | 02/10/2022 | Mexicali FC | - | Tecos Fútbol Club | 0:3 | ||||
| 9. Round | 08/10/2022 | Tritones Vallarta | - | Mexicali FC | 2:0 | ||||
| 10. Round | 16/10/2022 | Mexicali FC | - | Coras de Nayarit | 1:1 |  |
Mexico