| 1. Round | 24/02/2013 | Nacional | - | Defensor Sporting | 0:1 | ||||
| 2. Round | 03/03/2013 | Defensor Sporting | - | Montevideo Wanderers | 1:0 | ||||
| 3. Round | 09/03/2013 | Liverpool | - | Defensor Sporting | 4:2 | ||||
| 4. Round | 17/03/2013 | Defensor Sporting | - | Progreso | 0:1 | ||||
| 6. Round | 31/03/2013 | Defensor Sporting | - | El Tanque Sisley | 3:0 | ||||
| 7. Round | 07/04/2013 | Racing | - | Defensor Sporting | 0:0 | ||||
| 9. Round | 21/04/2013 | Defensor Sporting | - | Central Español | 2:1 | ||||
| 10. Round | 28/04/2013 | Defensor Sporting | - | Peñarol | 1:0 | ||||
| 12. Round | 12/05/2013 | Bella Vista | - | Defensor Sporting | 0:0 | ||||
| 13. Round | 18/05/2013 | Defensor Sporting | - | River Plate | 2:2 | ||||
| 14. Round | 26/05/2013 | Cerro Largo | - | Defensor Sporting | 0:1 | ||||
| 15. Round | 01/06/2013 | CA Cerro | - | Defensor Sporting | 1:1 |
Uruguay