| 1. Round | 15/02/2020 | Montevideo Wanderers | - | Defensor Sporting | 0:0 | ||||
| 2. Round | 23/02/2020 | Defensor Sporting | - | Peñarol | 2:1 |  |
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| 3. Round | 08/03/2020 | River Plate | - | Defensor Sporting | 1:1 | |
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| 4. Round | 08/08/2020 | Defensor Sporting | - | Montevideo City Torque | 0:2 | ||||
| 5. Round | 14/08/2020 | Plaza Colonia | - | Defensor Sporting | 2:0 | ||||
| 6. Round | 19/08/2020 | Defensor Sporting | - | Progreso | 2:1 | |
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| 7. Round | 23/08/2020 | Fénix | - | Defensor Sporting | 5:0 | ||||
| 8. Round | 27/08/2020 | Defensor Sporting | - | CA Cerro | 1:1 | ||||
| 10. Round | 06/09/2020 | Danubio | - | Defensor Sporting | 0:0 | ||||
| 11. Round | 11/09/2020 | Defensor Sporting | - | Nacional | 1:1 | ||||
| 12. Round | 13/09/2020 | Boston River | - | Defensor Sporting | 1:1 | ||||
| 13. Round | 19/09/2020 | Defensor Sporting | - | Deportivo Maldonado | 4:2 | ||||
| 14. Round | 07/10/2020 | Rentistas | - | Defensor Sporting | 2:0 | ||||
| 15. Round | 11/10/2020 | Defensor Sporting | - | Cerro Largo | 2:0 |
Uruguay