| 1. Round | 07/11/2021 | Levadiakos | - | Asteras Vlachioti | 2:1 | ||||
| 2. Round | 14/11/2021 | Asteras Vlachioti | - | AS Rhodos | 0:0 | ||||
| 3. Round | 20/11/2021 | AO Episkopi | - | Asteras Vlachioti | 0:1 | ||||
| 4. Round | 24/11/2021 | Asteras Vlachioti | - | AE Kifisias | 0:1 | ||||
| 16. Round | 29/01/2022 | AO Egaleo | - | Asteras Vlachioti | 1:0 | ||||
| 11. Round | 02/02/2022 | Asteras Vlachioti | - | Diagoras FC | 2:0 | ||||
| 17. Round | 06/02/2022 | Asteras Vlachioti | - | Irodotos | 1:3 | ||||
| 12. Round | 09/02/2022 | PAE Chania | - | Asteras Vlachioti | 3:1 |  |
|||
| 18. Round | 13/02/2022 | Asteras Vlachioti | - | Levadiakos | 1:2 |
Ghana