| 1. Round | 29/08/2021 | Bnei Sachnin FC | - | Maccabi Tel Aviv | 3:1 |  |
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| 2. Round | 11/09/2021 | Maccabi Tel Aviv | - | Maccabi Petach-Tikva | 1:1 | ||||
| 5. Round | 03/10/2021 | Maccabi Tel Aviv | - | Hapoel Jerusalem | 1:0 | ||||
| 6. Round | 16/10/2021 | Maccabi Netanya | - | Maccabi Tel Aviv | 4:2 | ||||
| 8. Round | 30/10/2021 | Ironi Kiryat Shmona | - | Maccabi Tel Aviv | 1:3 | ||||
| 9. Round | 07/11/2021 | Maccabi Tel Aviv | - | Hapoel Tel Aviv | 1:1 | ||||
| 10. Round | 28/11/2021 | Hapoel Haifa | - | Maccabi Tel Aviv | 1:3 | ||||
| 11. Round | 01/12/2021 | Maccabi Tel Aviv | - | Hapoel Nof HaGalil | 1:1 |  |
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| 15. Round | 27/12/2021 | Maccabi Petach-Tikva | - | Maccabi Tel Aviv | 1:2 | ||||
| 16. Round | 03/01/2022 | Maccabi Haifa | - | Maccabi Tel Aviv | 3:2 | |
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| 17. Round | 08/01/2022 | Maccabi Tel Aviv | - | Hapoel Be'er Sheva | 1:0 | ||||
| 21. Round | 05/02/2022 | Maccabi Tel Aviv | - | Ironi Kiryat Shmona | 1:0 | |
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| 22. Round | 12/02/2022 | Hapoel Tel Aviv | - | Maccabi Tel Aviv | 2:3 | ||||
| 24. Round | 28/02/2022 | Hapoel Nof HaGalil | - | Maccabi Tel Aviv | 1:3 | ||||
| 25. Round | 07/03/2022 | Maccabi Tel Aviv | - | Beitar Jerusalem | 3:1 | ||||
| 26. Round | 12/03/2022 | Hapoel Hadera | - | Maccabi Tel Aviv | 0:2 |
Spain