| 3. Round | 30/01/2019 | The Strongest | - | Real Potosí | 4:1 |  |
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| 5. Round | 07/02/2019 | Jorge Wilstermann | - | Real Potosí | 5:0 | ||||
| 6. Round | 11/02/2019 | Real Potosí | - | Destroyers | 3:2 | ||||
| 7. Round | 17/02/2019 | Club San José | - | Real Potosí | 2:2 | ||||
| 8. Round | 20/02/2019 | Real Potosí | - | Nacional Potosí | 1:3 | ||||
| 9. Round | 23/02/2019 | Blooming | - | Real Potosí | 5:3 | ||||
| 10. Round | 28/02/2019 | Real Potosí | - | Bolívar | 2:2 | ||||
| 11. Round | 09/03/2019 | Always Ready | - | Real Potosí | 3:1 | ||||
| 12. Round | 13/03/2019 | Real Potosí | - | Club Aurora | 2:2 | ||||
| 13. Round | 17/03/2019 | Royal Pari | - | Real Potosí | 4:1 | ||||
| 14. Round | 31/03/2019 | CD Guabirá | - | Real Potosí | 2:1 | ||||
| 15. Round | 04/04/2019 | Oriente Petrolero | - | Real Potosí | 2:1 |  |
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| 16. Round | 07/04/2019 | Real Potosí | - | The Strongest | 0:2 | ||||
| 22. Round | 05/05/2019 | Real Potosí | - | Blooming | 2:2 | ||||
| 25. Round | 19/05/2019 | Club Aurora | - | Real Potosí | 3:2 | ||||
| 26. Round | 25/05/2019 | Real Potosí | - | Royal Pari | 3:1 |
Bolivia