| 1. Round | 04/03/2018 | Philadelphia Union | - | New England Revolution | 2:0 | ||||
| 1. Round | 17/03/2018 | Philadelphia Union | - | Columbus Crew | 0:0 | ||||
| 3. Round | 10/05/2018 | Columbus Crew | - | Philadelphia Union | 1:0 | ||||
| 3. Round | 12/05/2018 | Impact de Montréal | - | Philadelphia Union | 0:2 | ||||
| 4. Round | 03/06/2018 | Atlanta United FC | - | Philadelphia Union | 3:1 | ||||
| 5. Round | 22/07/2018 | Philadelphia Union | - | Los Angeles Galaxy | 1:3 | ||||
| 6. Round | 05/08/2018 | Portland Timbers | - | Philadelphia Union | 3:0 | ||||
| 7. Round | 20/09/2018 | Seattle Sounders | - | Philadelphia Union | 0:1 | ||||
| 7. Round | 23/09/2018 | Philadelphia Union | - | Sporting Kansas City | 2:0 | ||||
| 7. Round | 30/09/2018 | Columbus Crew | - | Philadelphia Union | 0:0 |  |
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| 8. Round | 28/10/2018 | New York City FC | - | Philadelphia Union | 3:1 |
Brazil