| 2. Round | 12/09/2020 | SK Dnipro-1 | - | Olimpik Donetsk | 1:3 | ||||
| 3. Round | 20/09/2020 | Olimpik Donetsk | - | FC Mynai | 3:0 | ||||
| 4. Round | 27/09/2020 | Shakhtar Donetsk | - | Olimpik Donetsk | 2:0 | ||||
| 6. Round | 18/10/2020 | Olimpik Donetsk | - | Vorskla Poltava | 0:1 |  |
|||
| 7. Round | 24/10/2020 | Olimpik Donetsk | - | Desna Chernigov | 0:2 | ||||
| 8. Round | 31/10/2020 | Kolos Kovalivka | - | Olimpik Donetsk | 1:2 | ||||
| 12. Round | 06/12/2020 | Olimpik Donetsk | - | Rukh Lviv | 3:1 | ||||
| 13. Round | 11/12/2020 | Olimpik Donetsk | - | FK Lviv | 1:1 | |
|||
| 14. Round | 13/02/2021 | Dinamo Kiev | - | Olimpik Donetsk | 3:1 |  |
|||
| 15. Round | 22/02/2021 | Olimpik Donetsk | - | SK Dnipro-1 | 0:2 | ||||
| 18. Round | 14/03/2021 | FK Oleksandriya | - | Olimpik Donetsk | 2:0 | ||||
| 19. Round | 20/03/2021 | Vorskla Poltava | - | Olimpik Donetsk | 3:0 | ||||
| 21. Round | 11/04/2021 | Olimpik Donetsk | - | Kolos Kovalivka | 1:2 | ||||
| 25. Round | 06/05/2021 | Rukh Lviv | - | Olimpik Donetsk | 3:0 | ||||
| 26. Round | 09/05/2021 | FK Lviv | - | Olimpik Donetsk | 1:1 | |
Argentina