| 2. Round | 17/01/2023 | Club León | - | Club Necaxa | 2:1 |  |
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| 3. Round | 22/01/2023 | Club Necaxa | - | Cruz Azul | 1:0 |  |
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| 4. Round | 30/01/2023 | CF Pachuca | - | Club Necaxa | 2:1 | |
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| 5. Round | 04/02/2023 | Club Necaxa | - | Club Tijuana | 1:1 | ||||
| 6. Round | 11/02/2023 | CF América | - | Club Necaxa | 2:1 | ||||
| 7. Round | 16/02/2023 | Club Necaxa | - | Pumas UNAM | 3:1 | ||||
| 8. Round | 18/02/2023 | CF Monterrey | - | Club Necaxa | 2:1 | ||||
| 11. Round | 13/03/2023 | FC Juárez | - | Club Necaxa | 1:1 | ||||
| 12. Round | 18/03/2023 | Mazatlán FC | - | Club Necaxa | 0:1 | ||||
| 13. Round | 01/04/2023 | Club Necaxa | - | Santos Laguna | 0:0 | ||||
| 14. Round | 09/04/2023 | Deportivo Guadalajara | - | Club Necaxa | 1:0 |
Uruguay