| 1. Round | 09/07/2022 | Pumas UNAM [Women] | - | Mazatlán FC [Women] | 3:0 | ||||
| 2. Round | 17/07/2022 | Mazatlán FC [Women] | - | FC Juárez [Women] | 1:2 | ||||
| 11. Round | 13/09/2022 | Mazatlán FC [Women] | - | Deportivo Toluca [Women] | 3:1 | ||||
| 12. Round | 17/09/2022 | Cruz Azul [Women] | - | Mazatlán FC [Women] | 1:0 | ||||
| 13. Round | 23/09/2022 | Mazatlán FC [Women] | - | Club Tijuana [Women] | 0:5 | ||||
| 14. Round | 27/09/2022 | Santos Laguna [Women] | - | Mazatlán FC [Women] | 3:2 | ||||
| 15. Round | 03/10/2022 | Mazatlán FC [Women] | - | Atlético San Luis [Women] | 1:3 | ||||
| 16. Round | 15/10/2022 | Atlas Guadalajara [Women] | - | Mazatlán FC [Women] | 5:0 | ||||
| 17. Round | 25/10/2022 | Mazatlán FC [Women] | - | CF Pachuca [Women] | 3:1 |
Mexico