| 5. Round | 02/02/2025 | Santos Laguna | - | Puebla FC | 0:2 | ||||
| 6. Round | 08/02/2025 | Puebla FC | - | CF América | 1:2 |  |
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| 7. Round | 15/02/2025 | Atlas Guadalajara | - | Puebla FC | 3:2 | |
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| 10. Round | 02/03/2025 | Gallos Blancos | - | Puebla FC | 2:0 | ||||
| 12. Round | 15/03/2025 | Puebla FC | - | Deportivo Toluca | 0:3 | ||||
| 15. Round | 13/04/2025 | Club León | - | Puebla FC | 1:0 |
USA
Mexico