| 5. Round | 10/08/2019 | San Lorenzo | - | Deportivo Capiatá | 1:1 | ||||
| 6. Round | 16/08/2019 | San Lorenzo | - | General Díaz | 1:1 | ||||
| 7. Round | 24/08/2019 | Guaraní | - | San Lorenzo | 3:1 | ||||
| 9. Round | 15/09/2019 | Club Olimpia | - | San Lorenzo | 4:1 | ||||
| 10. Round | 21/09/2019 | San Lorenzo | - | Club Nacional | 0:3 | ||||
| 11. Round | 24/09/2019 | River Plate | - | San Lorenzo | 0:0 | ||||
| 12. Round | 30/09/2019 | Libertad | - | San Lorenzo | 3:0 | ||||
| 19. Round | 27/11/2019 | Sol de América | - | San Lorenzo | 1:0 | ||||
| 20. Round | 01/12/2019 | San Lorenzo | - | Club Olimpia | 1:4 | ||||
| 21. Round | 09/12/2019 | Club Nacional | - | San Lorenzo | 4:2 |
Paraguay