| 1. Round | 07/01/2023 | CF Monterrey [U20] | - | Deportivo Guadalajara [U20] | 1:2 | ||||
| 2. Round | 13/01/2023 | Atlético San Luis [U20] | - | Deportivo Guadalajara [U20] | 0:1 |  |
|||
| 3. Round | 21/01/2023 | Deportivo Guadalajara [U20] | - | Deportivo Toluca [U20] | 2:1 | |
|||
| 4. Round | 28/01/2023 | FC Juárez [U20] | - | Deportivo Guadalajara [U20] | 0:1 | ||||
| 5. Round | 05/02/2023 | Deportivo Guadalajara [U20] | - | Gallos Blancos [U20] | 3:2 | ||||
| 8. Round | 18/02/2023 | Pumas UNAM [U20] | - | Deportivo Guadalajara [U20] | 2:3 | |
|||
| 15. Round | 15/04/2023 | Club León [U20] | - | Deportivo Guadalajara [U20] | 2:2 | ||||
| 17. Round | 29/04/2023 | Deportivo Guadalajara [U20] | - | Mazatlán FC [U20] | 5:1 |
Mexico