| 4. Round | 11/08/2020 | UANL Tigres [U20] | - | Puebla FC [U20] | 1:1 | ||||
| 5. Round | 14/08/2020 | Puebla FC [U20] | - | CF Pachuca [U20] | 0:0 | ||||
| 6. Round | 23/08/2020 | Club Tijuana [U20] | - | Puebla FC [U20] | 1:1 | ||||
| 9. Round | 08/09/2020 | Puebla FC [U20] | - | CF América [U20] | 3:1 | ||||
| 10. Round | 11/09/2020 | FC Juárez [U20] | - | Puebla FC [U20] | 2:0 | ||||
| 11. Round | 18/09/2020 | Club Necaxa [U20] | - | Puebla FC [U20] | 1:1 | ||||
| 12. Round | 25/09/2020 | Puebla FC [U20] | - | Gallos Blancos [U20] | 3:2 | ||||
| 16. Round | 31/10/2020 | Atlas Guadalajara [U20] | - | Puebla FC [U20] | 1:0 |
Mexico