| 4. Round | 17/08/2024 | 1. FC Bocholt | - | FC Schalke 04 II | 3:1 | ||||
| 5. Round | 24/08/2024 | FC Schalke 04 II | - | 1. FC Düren | 1:4 |  |
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| 6. Round | 01/09/2024 | 1. FC Köln II | - | FC Schalke 04 II | 4:0 | ||||
| 9. Round | 28/09/2024 | FC Schalke 04 II | - | MSV Duisburg | 1:2 | ||||
| 19. Round | 25/01/2025 | KFC Uerdingen 05 | - | FC Schalke 04 II | annull. | ||||
| 20. Round | 01/02/2025 | SV Rödinghausen | - | FC Schalke 04 II | 0:0 | ||||
| 23. Round | 23/02/2025 | FC Schalke 04 II | - | 1. FC Köln II | 1:0 | ||||
| 24. Round | 28/02/2025 | Bor. Mönchengladbach II | - | FC Schalke 04 II | 0:0 | ||||
| 25. Round | 08/03/2025 | FC Schalke 04 II | - | Wuppertaler SV | 1:0 |
Germany