| 6. Round | 10/09/2021 | AZ Alkmaar (J) | - | FC Utrecht (J) | 0:1 | ||||
| 8. Round | 24/09/2021 | Telstar | - | AZ Alkmaar (J) | 1:0 | ||||
| 16. Round | 19/11/2021 | Roda JC Kerkrade | - | AZ Alkmaar (J) | 2:2 | ||||
| 15. Round | 22/11/2021 | AZ Alkmaar (J) | - | FC Emmen | 0:0 |  |
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| 17. Round | 26/11/2021 | FC Eindhoven | - | AZ Alkmaar (J) | 1:0 | ||||
| 25. Round | 04/02/2022 | Jong Ajax | - | AZ Alkmaar (J) | 2:1 | ||||
| 26. Round | 11/02/2022 | FC Volendam | - | AZ Alkmaar (J) | 2:1 | |
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| 24. Round | 21/02/2022 | AZ Alkmaar (J) | - | NAC Breda | 0:2 | ||||
| 28. Round | 25/02/2022 | AZ Alkmaar (J) | - | FC Eindhoven | 1:3 | ||||
| 29. Round | 04/03/2022 | De Graafschap | - | AZ Alkmaar (J) | 0:0 | ||||
| 30. Round | 07/03/2022 | AZ Alkmaar (J) | - | Telstar | 3:2 | ||||
| 27. Round | 14/03/2022 | MVV | - | AZ Alkmaar (J) | 2:3 | ||||
| 33. Round | 01/04/2022 | AZ Alkmaar (J) | - | Jong PSV | 2:0 | ||||
| 32. Round | 04/04/2022 | AZ Alkmaar (J) | - | Roda JC Kerkrade | 0:1 | |
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| 34. Round | 08/04/2022 | FC Emmen | - | AZ Alkmaar (J) | 3:0 |
Netherlands