| 6. Round | 24/10/2020 | Alacranes de Durango | - | Cimarrones de Sonora II | 0:0 | ||||
| 7. Round | 17/11/2020 | Saltillo FC | - | Alacranes de Durango | 1:2 | ||||
| 9. Round | 21/11/2020 | Tecos Fútbol Club | - | Alacranes de Durango | 0:2 |  |
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| 12. Round | 16/01/2021 | Atlético San Luis II | - | Alacranes de Durango | 1:1 |  |
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| 18. Round | 06/03/2021 | Alacranes de Durango | - | Saltillo FC | 3:1 | ||||
| 21. Round | 03/04/2021 | Mineros de Fresnillo FC | - | Alacranes de Durango | 0:1 | ||||
| 22. Round | 10/04/2021 | Alacranes de Durango | - | Mazorqueros | 4:0 |
Mexico