| 13. Round | 30/07/2022 | Villa Española | - | Progreso | 0:0 |  |
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| 14. Round | 06/08/2022 | Progreso | - | Juventud de Las Piedras | 0:1 | ||||
| 16. Round | 20/08/2022 | Progreso | - | Rampla Juniors | 0:1 | ||||
| 18. Round | 28/08/2022 | La Luz | - | Progreso | 1:1 | ||||
| 19. Round | 03/09/2022 | Progreso | - | Atenas | 1:0 | ||||
| 20. Round | 10/09/2022 | CA Cerro | - | Progreso | 1:1 | ||||
| 21. Round | 17/09/2022 | Progreso | - | Sud América | 3:1 | ||||
| 22. Round | 25/09/2022 | Central Español | - | Progreso | 1:1 |
Uruguay