| 2. Round | 13/09/2021 | AEL Limassol | - | Paphos FC | 4:0 |  |
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| 3. Round | 18/09/2021 | Olympiakos Nikosia | - | AEL Limassol | 1:1 | ||||
| 5. Round | 01/10/2021 | PAEEK | - | AEL Limassol | 1:3 | |
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| 6. Round | 17/10/2021 | AEL Limassol | - | Anorthosis Famagusta | 2:1 | ||||
| 7. Round | 23/10/2021 | Ethnikos Achna | - | AEL Limassol | 2:2 | |
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| 8. Round | 30/10/2021 | AEL Limassol | - | Aris Limassol | 0:1 | ||||
| 9. Round | 06/11/2021 | APOEL Nikosia | - | AEL Limassol | 3:0 | ||||
| 10. Round | 21/11/2021 | Doxa Katokopias | - | AEL Limassol | 0:0 | ||||
| 12. Round | 05/12/2021 | AEL Limassol | - | Omonia Nikosia | 0:1 | ||||
| 13. Round | 10/12/2021 | Paphos FC | - | AEL Limassol | 1:0 |  |
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| 14. Round | 19/12/2021 | AEL Limassol | - | Olympiakos Nikosia | 3:0 | ||||
| 1. Round | 22/12/2021 | Omonia Nikosia | - | AEL Limassol | 1:0 |
Argentina