2. Round | 22/02/2022 | San Luis | - | CD Magallanes | 0:2 | ||||
3. Round | 03/03/2022 | Barnechea | - | San Luis | 3:1 | ||||
4. Round | 09/03/2022 | San Luis | - | Santiago Wanderers | 1:1 | ||||
5. Round | 16/03/2022 | San Luis | - | Santiago Morning | 1:2 | ||||
6. Round | 23/03/2022 | Rangers | - | San Luis | 2:3 | ||||
8. Round | 12/04/2022 | Unión San Felipe | - | San Luis | 2:0 | ||||
9. Round | 18/04/2022 | San Luis | - | Melipilla | 2:1 | ||||
10. Round | 21/04/2022 | Puerto Montt | - | San Luis | 1:1 | ||||
12. Round | 30/04/2022 | San Luis | - | Deportes Temuco | 1:1 | ||||
13. Round | 07/05/2022 | Deportes Iquique | - | San Luis | 1:1 | ||||
14. Round | 13/05/2022 | San Luis | - | Fernández Vial | 0:0 | ||||
15. Round | 18/05/2022 | Santa Cruz | - | San Luis | 2:0 | ||||
16. Round | 23/05/2022 | Recoleta | - | San Luis | 2:3 | ||||
19. Round | 09/07/2022 | CD Magallanes | - | San Luis | 3:0 | ||||
24. Round | 16/08/2022 | Copiapó | - | San Luis | 1:1 | ||||
26. Round | 31/08/2022 | Melipilla | - | San Luis | 1:2 | ||||
29. Round | 27/09/2022 | Deportes Temuco | - | San Luis | 1:0 | ||||
31. Round | 10/10/2022 | Fernández Vial | - | San Luis | 1:1 |