| 4. Round | 10/02/2025 | Atlético Tembetary | - | General Caballero DJLM | 1:0 |  |
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| 5. Round | 14/02/2025 | General Caballero DJLM | - | Sportivo Luqueño | 3:0 | |
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| 9. Round | 14/03/2025 | 2 de Mayo | - | General Caballero DJLM | 0:1 | ||||
| 11. Round | 30/03/2025 | Club Nacional | - | General Caballero DJLM | 1:0 | ||||
| 13. Round | 14/04/2025 | General Caballero DJLM | - | Guaraní | 0:0 | ||||
| 14. Round | 16/04/2025 | Sportivo Ameliano | - | General Caballero DJLM | 0:1 |  |
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| 15. Round | 20/04/2025 | General Caballero DJLM | - | Atlético Tembetary | 0:1 | ||||
| 16. Round | 27/04/2025 | Sportivo Luqueño | - | General Caballero DJLM | 0:0 | ||||
| 17. Round | 05/05/2025 | General Caballero DJLM | - | Sportivo Trinidense | 1:1 | ||||
| 18. Round | 11/05/2025 | Club Olimpia | - | General Caballero DJLM | 0:3 | ||||
| 19. Round | 16/05/2025 | Cerro Porteño | - | General Caballero DJLM | 2:1 | ||||
| 20. Round | 21/05/2025 | General Caballero DJLM | - | 2 de Mayo | 1:1 | ||||
| 21. Round | 24/05/2025 | Libertad | - | General Caballero DJLM | 1:0 | ||||
| 22. Round | 30/05/2025 | General Caballero DJLM | - | Club Nacional | 2:4 |
Paraguay