| 1. Round | 18/01/2004 | Santos Laguna | - | Deportivo Guadalajara | 0:1 | ||||
| 2. Round | 25/01/2004 | Club Necaxa | - | Santos Laguna | 2:2 | ||||
| 4. Round | 08/02/2004 | Pumas UNAM | - | Santos Laguna | 3:2 |  |
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| 6. Round | 21/02/2004 | Veracruz (old) | - | Santos Laguna | 2:1 | ||||
| 9. Round | 07/03/2004 | Santos Laguna | - | CF América | 0:1 | ||||
| 13. Round | 04/04/2004 | Atlante | - | Santos Laguna | 2:1 | ||||
| 16. Round | 25/04/2004 | Santos Laguna | - | Monarcas Morelia | 6:0 | ||||
| 17. Round | 01/05/2004 | Gallos Blancos (old) | - | Santos Laguna | 2:0 |
Mexico