| 2. Round | 13/01/2023 | Atlético San Luis [U20] | - | Deportivo Guadalajara [U20] | 0:1 | ||||
| 3. Round | 21/01/2023 | CF Monterrey [U20] | - | Atlético San Luis [U20] | 1:1 | ||||
| 4. Round | 28/01/2023 | UANL Tigres [U20] | - | Atlético San Luis [U20] | 0:0 | ||||
| 5. Round | 02/02/2023 | Atlético San Luis [U20] | - | Puebla FC [U20] | 3:1 | ||||
| 6. Round | 10/02/2023 | Club Tijuana [U20] | - | Atlético San Luis [U20] | 2:1 | ||||
| 7. Round | 14/02/2023 | Atlético San Luis [U20] | - | CF América [U20] | 1:2 | ||||
| 8. Round | 18/02/2023 | Atlético San Luis [U20] | - | Santos Laguna [U20] | 0:1 | ||||
| 9. Round | 26/02/2023 | Deportivo Toluca [U20] | - | Atlético San Luis [U20] | 3:0 | ||||
| 10. Round | 04/03/2023 | Club León [U20] | - | Atlético San Luis [U20] | 1:1 | ||||
| 11. Round | 10/03/2023 | Atlético San Luis [U20] | - | Gallos Blancos [U20] | 1:4 | ||||
| 12. Round | 18/03/2023 | Cruz Azul [U20] | - | Atlético San Luis [U20] | 1:0 | ||||
| 13. Round | 02/04/2023 | Atlético San Luis [U20] | - | Mazatlán FC [U20] | 1:1 | ||||
| 14. Round | 09/04/2023 | Pumas UNAM [U20] | - | Atlético San Luis [U20] | 3:2 | ||||
| 15. Round | 13/04/2023 | Atlético San Luis [U20] | - | FC Juárez [U20] | 2:2 |  |
Mexico