| 1. Round | 09/03/2025 | Lexington SC | - | Hartford Athletic | 2:0 | ||||
| 2. Round | 16/03/2025 | Orange County SC | - | Lexington SC | 2:2 | ||||
| 3. Round | 22/03/2025 | Lexington SC | - | Indy Eleven | 1:1 | ||||
| 4. Round | 29/03/2025 | Lexington SC | - | San Antonio FC | 2:3 | ||||
| 6. Round | 13/04/2025 | Lexington SC | - | Las Vegas Lights FC | 0:0 | ||||
| 7. Round | 20/04/2025 | Lexington SC | - | Monterey Bay FC | 0:0 | ||||
| 8. Round | 02/05/2025 | Louisville City FC | - | Lexington SC | 2:0 | ||||
| 9. Round | 10/05/2025 | Loudoun United | - | Lexington SC | 5:1 | ||||
| 13. Round | 15/06/2025 | Lexington SC | - | New Mexico United | 2:1 | ||||
| 14. Round | 21/06/2025 | Lexington SC | - | Colorado Springs Switchbacks | 2:1 |
France