| Group 7 | 19/04/2018 | Independiente | - | Corinthians SP | 0:1 | ||||
| Group 7 | 03/05/2018 | Corinthians SP | - | Independiente | 1:2 | ||||
| Group 7 | 18/05/2018 | Millonarios | - | Independiente | 1:1 | ||||
| Group 7 | 25/05/2018 | Independiente | - | Deportivo Lara | 2:0 |  |
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| Round of 16 | 22/08/2018 | Independiente | - | Santos FC | 3:0 dec. | |
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| Round of 16 | 28/08/2018 | Santos FC | - | Independiente | 0:0 | ||||
| Quarter-finals | 19/09/2018 | Independiente | - | River Plate | 0:0 | ||||
| Quarter-finals | 02/10/2018 | River Plate | - | Independiente | 3:1 |
Uruguay
Italy