| 1. Round | 24/08/2015 | Panetolikos | - | Panathinaikos | 1:2 |  |
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| 3. Round | 13/09/2015 | Panionios GSS | - | Panathinaikos | 1:0 | ||||
| 4. Round | 23/09/2015 | Panathinaikos | - | Levadiakos | 3:0 | ||||
| 5. Round | 27/09/2015 | Panathinaikos | - | Platanias Chanion | 1:0 | ||||
| 7. Round | 19/10/2015 | Panathinaikos | - | PAS Giannina | 3:1 | ||||
| 8. Round | 25/10/2015 | PAOK Saloniki | - | Panathinaikos | 3:1 | ||||
| 9. Round | 01/11/2015 | Panathinaikos | - | AEK Athen | 0:0 | ||||
| 14. Round | 13/12/2015 | Panathinaikos | - | Asteras Tripolis | 2:0 | ||||
| 15. Round | 20/12/2015 | Panthrakikos | - | Panathinaikos | 1:0 |  |
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| 17. Round | 11/01/2016 | AEL Kalloni | - | Panathinaikos | 0:2 | ||||
| 18. Round | 17/01/2016 | Panathinaikos | - | Panionios GSS | 0:0 | ||||
| 19. Round | 24/01/2016 | Levadiakos | - | Panathinaikos | 0:2 | ||||
| 22. Round | 14/02/2016 | PAS Giannina | - | Panathinaikos | 0:3 | ||||
| 23. Round | 21/02/2016 | Panathinaikos | - | PAOK Saloniki | 2:2 | |
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| 24. Round | 28/02/2016 | AEK Athen | - | Panathinaikos | 1:0 | |
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| 25. Round | 06/03/2016 | Panathinaikos | - | Atromitos | 2:0 | ||||
| 26. Round | 13/03/2016 | Olympiakos Piraeus | - | Panathinaikos | 3:1 | ||||
| 27. Round | 19/03/2016 | Panathinaikos | - | AEP Iraklis FC | 4:0 |
Greece