| 2. Round | 08/09/2024 | Deportivo Maldonado | - | River Plate | 0:1 | ||||
| 3. Round | 15/09/2024 | Danubio | - | River Plate | 3:0 | ||||
| 4. Round | 22/09/2024 | Boston River | - | River Plate | 3:1 | ||||
| 5. Round | 29/09/2024 | River Plate | - | Fénix | 4:3 | ||||
| 7. Round | 13/10/2024 | Montevideo Wanderers | - | River Plate | 0:1 | ||||
| 9. Round | 19/10/2024 | Progreso | - | River Plate | 2:0 | ||||
| 10. Round | 03/11/2024 | River Plate | - | Peñarol | 0:1 | ||||
| 11. Round | 09/11/2024 | Cerro Largo | - | River Plate | 1:0 |  |
Uruguay