| 6. Round | 19/09/1980 | FC Den Haag | - | PEC Zwolle | 2:3 | ||||
| 7. Round | 26/09/1980 | PEC Zwolle | - | AZ '67 Alkmaar | 0:3 | ||||
| 8. Round | 05/10/1980 | Sparta Rotterdam | - | PEC Zwolle | 4:1 | ||||
| 10. Round | 25/10/1980 | PEC Zwolle | - | AFC Ajax | 2:0 | ||||
| 23. Round | 13/03/1981 | PEC Zwolle | - | FC Den Haag | 4:2 | ||||
| 24. Round | 27/03/1981 | AZ '67 Alkmaar | - | PEC Zwolle | 1:0 | ||||
| 29. Round | 02/05/1981 | FC Twente | - | PEC Zwolle | 2:0 | ||||
| 32. Round | 22/05/1981 | PEC Zwolle | - | FC Utrecht | 0:3 | ||||
| 33. Round | 29/05/1981 | Go Ahead Eagles | - | PEC Zwolle | 3:3 | ||||
| 34. Round | 05/06/1981 | PEC Zwolle | - | Roda JC Kerkrade | 3:0 |
Netherlands