| 3. Round | 28/01/2021 | Alebrijes de Oaxaca | - | Tapatío | 2:1 | ||||
| 1. Round | 06/02/2021 | Venados FC | - | Alebrijes de Oaxaca | 2:2 |  |
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| 5. Round | 09/02/2021 | Alebrijes de Oaxaca | - | Pumas Tabasco | 3:1 | ||||
| 6. Round | 20/02/2021 | Atlético Morelia | - | Alebrijes de Oaxaca | 6:3 | ||||
| 10. Round | 18/03/2021 | Atlante | - | Alebrijes de Oaxaca | 1:1 | ||||
| 11. Round | 24/03/2021 | Alebrijes de Oaxaca | - | Cancún FC | 0:0 | |
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| 12. Round | 27/03/2021 | Club Celaya | - | Alebrijes de Oaxaca | 0:0 |
Mexico