| 1. Round | 09/07/2017 | FC Sheriff | - | FC Zaria | 5:0 | ||||
| 2. Round | 16/07/2017 | Dacia Chişinău | - | FC Sheriff | 1:1 | ||||
| 3. Round | 22/07/2017 | FC Sheriff | - | FC Zimbru | 2:2 | ||||
| 4. Round | 29/07/2017 | CS Petrocub | - | FC Sheriff | 1:2 | ||||
| 5. Round | 05/08/2017 | FC Sheriff | - | Dinamo-Auto | 3:1 | ||||
| 6. Round | 12/08/2017 | FC Sfîntul Gheorghe | - | FC Sheriff | 0:3 |  |
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| 8. Round | 27/08/2017 | FC Sheriff | - | FC Milsami | 3:1 | |
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| 9. Round | 10/09/2017 | Speranţa Nisporeni | - | FC Sheriff | 1:2 | ||||
| 10. Round | 17/09/2017 | FC Zaria | - | FC Sheriff | 0:2 | ||||
| 11. Round | 23/09/2017 | FC Sheriff | - | Dacia Chişinău | 6:3 | |
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| 12. Round | 01/10/2017 | FC Zimbru | - | FC Sheriff | 1:2 | |
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| 14. Round | 22/10/2017 | Dinamo-Auto | - | FC Sheriff | 0:4 | ||||
| 15. Round | 28/10/2017 | FC Sheriff | - | FC Sfîntul Gheorghe | 1:1 | |
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| 16. Round | 06/11/2017 | Spicul Chișcăreni | - | FC Sheriff | 0:4 | ||||
| 17. Round | 18/11/2017 | FC Milsami | - | FC Sheriff | 0:2 |
Moldova