| 6. Round | 24/07/2022 | Columbus Crew | - | New England Revolution | 0:0 | ||||
| 6. Round | 31/07/2022 | New England Revolution | - | Toronto FC | 0:0 | ||||
| 8. Round | 10/09/2022 | New York RB | - | New England Revolution | 2:1 | ||||
| 8. Round | 14/09/2022 | Houston Dynamo | - | New England Revolution | 3:1 | ||||
| 8. Round | 18/09/2022 | New England Revolution | - | CF Montréal | 0:1 | ||||
| 9. Round | 01/10/2022 | New England Revolution | - | Atlanta United FC | 2:1 |  |
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| 9. Round | 09/10/2022 | Chicago Fire | - | New England Revolution | 1:1 |  |
Italy