| 16. Round | 30/01/2022 | GS Kallithea | - | Diagoras FC | 1:0 | ||||
| 19. Round | 16/02/2022 | GS Kallithea | - | OFI Ierapetra | 1:2 | ||||
| 13. Round | 02/03/2022 | AE Karaiskakis | - | GS Kallithea | 1:0 | ||||
| 22. Round | 06/03/2022 | GS Kallithea | - | Irodotos | 3:0 |  |
|||
| 25. Round | 20/03/2022 | AO Episkopi | - | GS Kallithea | 1:1 |  |
|||
| 23. Round | 23/03/2022 | Levadiakos | - | GS Kallithea | 1:1 | ||||
| 30. Round | 10/04/2022 | GS Kallithea | - | AE Karaiskakis | 4:2 | ||||
| 32. Round | 17/04/2022 | GS Kallithea | - | Asteras Vlachioti | 5:1 | ||||
| 33. Round | 27/04/2022 | Diagoras FC | - | GS Kallithea | 0:0 |
Greece