| 1. Round | 11/09/2020 | PAOK Saloniki | - | AE Lárissa | 1:0 |  |
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| 2. Round | 18/09/2020 | PAOK Saloniki | - | Atromitos | 1:1 | ||||
| 4. Round | 04/10/2020 | PAOK Saloniki | - | OFI Heraklion | 3:0 | ||||
| 5. Round | 18/10/2020 | AEK Athen | - | PAOK Saloniki | 1:1 | |
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| 8. Round | 08/11/2020 | Apollon Smyrnis | - | PAOK Saloniki | 1:3 | ||||
| 10. Round | 29/11/2020 | Lamia | - | PAOK Saloniki | 0:2 | ||||
| 11. Round | 06/12/2020 | PAOK Saloniki | - | Asteras Tripolis | 2:0 | ||||
| 12. Round | 13/12/2020 | Aris Saloniki | - | PAOK Saloniki | 1:0 | ||||
| 13. Round | 20/12/2020 | PAOK Saloniki | - | Panathinaikos | 2:1 | |
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| 15. Round | 07/01/2021 | Atromitos | - | PAOK Saloniki | 3:2 | |
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| 23. Round | 21/02/2021 | PAOK Saloniki | - | Lamia | 4:0 | ||||
| 24. Round | 27/02/2021 | Asteras Tripolis | - | PAOK Saloniki | 2:1 |
Greece