| 6. Round | 19/09/2021 | Adanaspor | - | Ümraniyespor | 0:0 | ||||
| 7. Round | 25/09/2021 | BB Erzurumspor | - | Adanaspor | 3:1 | ||||
| 9. Round | 17/10/2021 | Manisa FK | - | Adanaspor | 0:3 | ||||
| 10. Round | 22/10/2021 | Eyüpspor | - | Adanaspor | 1:0 | ||||
| 11. Round | 01/11/2021 | Adanaspor | - | Altınordu FK | 1:0 | ||||
| 12. Round | 07/11/2021 | Balıkesirspor | - | Adanaspor | 1:2 | ||||
| 13. Round | 21/11/2021 | Adanaspor | - | MKE Ankaragücü | 1:0 | ||||
| 14. Round | 27/11/2021 | Samsunspor | - | Adanaspor | 1:0 | ||||
| 15. Round | 04/12/2021 | Adanaspor | - | Tuzlaspor | 1:1 | ||||
| 16. Round | 11/12/2021 | Boluspor | - | Adanaspor | 0:0 | ||||
| 17. Round | 16/12/2021 | Adanaspor | - | İstanbulspor AŞ | 1:0 | ||||
| 19. Round | 24/12/2021 | Adanaspor | - | Kocaelispor | 2:0 | ||||
| 21. Round | 17/01/2022 | Gençlerbirliği | - | Adanaspor | 0:3 | ||||
| 22. Round | 23/01/2022 | Adanaspor | - | Keçiörengücü | 0:1 | ||||
| 23. Round | 06/02/2022 | Menemen Belediyespor | - | Adanaspor | 2:1 | ||||
| 24. Round | 12/02/2022 | Adanaspor | - | Denizlispor | 0:0 | ||||
| 25. Round | 17/02/2022 | Ümraniyespor | - | Adanaspor | 2:1 | ||||
| 26. Round | 21/02/2022 | Adanaspor | - | BB Erzurumspor | 1:1 | ||||
| 28. Round | 06/03/2022 | Adanaspor | - | Manisa FK | 2:0 | ||||
| 29. Round | 21/03/2022 | Adanaspor | - | Eyüpspor | 1:1 |
Bosnia-Herzegovina