| 2. Round | 02/05/2021 | FC Tulsa | - | Sporting Kansas City 2 | 2:0 | ||||
| 2. Round | 08/05/2021 | Sporting Kansas City 2 | - | OKC Energy FC | 1:1 | ||||
| 2. Round | 15/05/2021 | Sporting Kansas City 2 | - | Colorado Springs Switchbacks | 0:4 | ||||
| 2. Round | 30/05/2021 | Sporting Kansas City 2 | - | El Paso Locomotive | 0:0 | ||||
| 3. Round | 03/06/2021 | Sporting Kansas City 2 | - | FC Tulsa | 4:1 |  |
|||
| 3. Round | 27/06/2021 | Memphis 901 | - | Sporting Kansas City 2 | 2:3 | ||||
| 5. Round | 22/08/2021 | Sporting Kansas City 2 | - | Indy Eleven | 1:1 |  |
|||
| 5. Round | 29/08/2021 | Sporting Kansas City 2 | - | Memphis 901 | 0:0 | ||||
| 7. Round | 02/10/2021 | Sporting Kansas City 2 | - | Birmingham Legion | 0:1 | ||||
| 7. Round | 14/10/2021 | Sporting Kansas City 2 | - | Atlanta United II | 0:3 dec. |
USA