| 1. Round | 17/03/2018 | Rio Grande Valley FC | - | Saint Louis FC | 1:1 | ||||
| 2. Round | 08/04/2018 | Colorado Springs Switchbacks | - | Rio Grande Valley FC | 2:1 | ||||
| 2. Round | 15/04/2018 | Seattle Sounders 2 | - | Rio Grande Valley FC | 3:2 |  |
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| 2. Round | 19/04/2018 | Portland Timbers 2 | - | Rio Grande Valley FC | 3:2 | ||||
| 4. Round | 05/06/2018 | Real Monarchs SLC | - | Rio Grande Valley FC | 2:0 | ||||
| 4. Round | 10/06/2018 | Rio Grande Valley FC | - | Portland Timbers 2 | 0:1 | ||||
| 4. Round | 17/06/2018 | OKC Energy FC | - | Rio Grande Valley FC | 3:1 |  |
Spain