| 1. Round | 01/02/2025 | Defensor Sporting | - | Boston River | 2:0 | ||||
| 2. Round | 09/02/2025 | Boston River | - | Montevideo City Torque | 0:0 | ||||
| 3. Round | 15/02/2025 | Peñarol | - | Boston River | 1:1 | ||||
| 6. Round | 18/03/2025 | River Plate | - | Boston River | 0:2 | ||||
| 7. Round | 22/03/2025 | Boston River | - | Racing | 1:3 | ||||
| 8. Round | 26/03/2025 | Plaza Colonia | - | Boston River | 0:1 | ||||
| 15. Round | 20/05/2025 | Boston River | - | CA Cerro | 0:0 |
Uruguay