| 1. Round | 03/02/2025 | CA Cerro | - | River Plate | 1:1 | ||||
| 2. Round | 08/02/2025 | River Plate | - | Defensor Sporting | 0:1 | ||||
| 7. Round | 23/03/2025 | Progreso | - | River Plate | 2:1 | ||||
| 8. Round | 26/03/2025 | Racing | - | River Plate | 1:0 |  |
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| 9. Round | 29/03/2025 | River Plate | - | Plaza Colonia | 1:2 | ||||
| 12. Round | 18/04/2025 | Cerro Largo | - | River Plate | 1:0 | |
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| 13. Round | 26/04/2025 | River Plate | - | Danubio | 1:0 | ||||
| 15. Round | 17/05/2025 | River Plate | - | Montevideo Wanderers | 0:1 |
Uruguay