2. Round | 18/04/2021 | San Luis | - | Rangers | 0:1 | ||||
3. Round | 26/04/2021 | Puerto Montt | - | San Luis | 2:1 | ||||
4. Round | 03/05/2021 | San Luis | - | Unión San Felipe | 1:2 | ||||
5. Round | 09/05/2021 | Deportes Iquique | - | San Luis | 0:0 | ||||
7. Round | 25/05/2021 | San Luis | - | Copiapó | 1:2 | ||||
8. Round | 30/05/2021 | Cobreloa | - | San Luis | 1:0 | ||||
9. Round | 07/06/2021 | San Luis | - | San Marcos | 0:1 | ||||
10. Round | 11/07/2021 | Santa Cruz | - | San Luis | 2:0 | ||||
11. Round | 15/07/2021 | Santiago Morning | - | San Luis | 0:0 | ||||
12. Round | 23/07/2021 | San Luis | - | Universidad de Concepción | 1:0 | ||||
13. Round | 01/08/2021 | Coquimbo Unido | - | San Luis | 0:1 | ||||
14. Round | 10/08/2021 | San Luis | - | CD Magallanes | 1:1 | ||||
23. Round | 02/10/2021 | San Luis | - | Cobreloa | 1:0 | ||||
24. Round | 08/10/2021 | San Marcos | - | San Luis | 1:2 | ||||
25. Round | 12/10/2021 | San Luis | - | Santa Cruz | 0:0 | ||||
26. Round | 20/10/2021 | San Luis | - | Santiago Morning | 2:2 | ||||
27. Round | 25/10/2021 | Universidad de Concepción | - | San Luis | 0:2 | ||||
28. Round | 31/10/2021 | San Luis | - | Coquimbo Unido | 0:0 | ||||
29. Round | 06/11/2021 | CD Magallanes | - | San Luis | 3:3 | ||||
30. Round | 12/11/2021 | San Luis | - | Barnechea | 2:1 |