| 1. Round | 18/09/2020 | Inter Playa | - | Cafessa Jalisco | 2:1 | ||||
| 4. Round | 10/10/2020 | Cafessa Jalisco | - | Azores de Hidalgo | 0:0 |  |
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| 20. Round | 28/02/2021 | Cafessa Jalisco | - | Club de Ciervos | 3:0 | ||||
| 21. Round | 05/03/2021 | Cañoneros Marina | - | Cafessa Jalisco | 2:3 | ||||
| 22. Round | 14/03/2021 | Cafessa Jalisco | - | Cruz Azul Hidalgo | 1:3 | ||||
| 23. Round | 21/03/2021 | CD Cuautla | - | Cafessa Jalisco | 0:2 |
Mexico